[fw] Programmable DNA Scissors Found for Bacterial Immune System

http://newscenter.lbl.gov/feature-stories/2012/06/28/programmable-dna-scissors/

Programmable DNA scissors: A double-RNA structure in the bacterial immune system has been discovered that directs Cas9 protein to cleave and destroy invading DNA at specific nucleotide sequences. This same dual RNA structure should be programmable for genome editing.

 

2 thoughts on “[fw] Programmable DNA Scissors Found for Bacterial Immune System”

  1. 我想你也参加了长春的会议,很遗憾,在最后一天晚上才联系到你。但是你的微薄不能私信,只能到博客留言。
    同时,一个小小评论,细菌的这种“获得性免疫机制”与甲基化有很密切的关系。

    • 对,这次会议上看到不少新东西,当然吐槽是我永恒的劣习。这个CRISPR,要说甲基化,但是归根结底,大概还是会往RNA上走的。而且这个所谓免疫机制呢,还有很多未解的地方。有一些review分析过里面具体的发生机制。

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