“RISC” of Bacteria and Archaea

Restriction-modification systems, abortive-phage phenotypes, toxin-antitoxins and other innate defense systems, in the past, have been shown in familiar chapters in typical microbiology textbook, while now what if I say in prokaryotes world “RISC” can serve a role for new kind of antiviral defense, in addition the “RNAi” can even be engineered and designed to lead … Read more

RNA switch — Witch

After my vacation in Taiwan this winter, I’ve returned and found an interesting paper [1] , out of thousands of RSS feeds in my google reader. This paper comes from Christina Smolke‘s lab, and I’ve confess that sometimes I cannot help hating her, because of the outstanding researches to make the promising RNA device alive. … Read more